Samsung appeals Apple injunction against Galaxy Tab

News

By Martyn Williams

June 28, 2012 01:14 PM ET

IDG News Service - Lawyers for Samsung Electronics have petitioned a U.S. court to suspend a preliminary injunction that blocks its Galaxy Tab 10.1 tablet computer from sale in the country.

The South Korean electronics company filed papers on Wednesday at the U.S. District Court for the Northern District of California asking that the order be suspended pending an appeal.

The filing came a day after Judge Lucy Koh barred sales of the tablet and any "product that is no more than colorably different from this specified product and embodies any design contained in U.S. Design Patent No. D504,889."

Koh also ordered Apple to post a bond for $2.6 million toward any damages sustained by Samsung if the injunction is subsequently found to be erroneously enjoined.

Samsung argued the injunction on a number of points, including that Apple's evidence against the Galaxy Tab 10.1 is "seven months or older." Such injunctions are typically granted to prevent prospective harm from sales of the allegedly offending product, but that doesn't exist pending more current data from Apple, the company argued in the filing.

"Samsung not only has a strong likelihood of success on appeal given the Court's issuance of a preliminary injunction based on a stale record, but, absent a stay, the injunction will cause Samsung significant harm due to impaired relationships with customers and carriers, while causing no demonstrable injury to Apple," Samsung argued in its filing.

Samsung's appeal represents the latest round in a patent battle between the two companies that centers over a handful of patents covering product design.

Apple first asked for an injunction against the Galaxy Tab 10.1 in July last year. Koh denied the injunction in December, ruling that Apple was likely to suffer irreparable harm as a result of Samsung infringing the '889 design patent but that the patent itself was likely invalid.

The ruling ended up in the appeals court, which upheld Judge Koh's initial finding of infringement and irreparable harm with respect to the '889 Patent, but disagreed with her finding on the validity of the patent. That appeals court finding opened the door to this week's injunction.

Martyn Williams covers mobile telecoms, Silicon Valley and general technology breaking news for The IDG News Service. Follow Martyn on Twitter at @martyn_williams. Martyn's e-mail address is martyn_williams@idg.com

Reprinted with permission from IDG.net. Story copyright 2012 International Data Group. All rights reserved.

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With New Mobile Apps, Eric Schmidt-Backed HealthTap Brings The House Call Back To Healthcare

Over 80 percent of people seek health-related information online, on everything from insurance to help diagnosing aches and pains. As the world goes mobile, so too does health. Instead of using Google for your health queries or perusing WebMD, HealthTap launched last year to give people a way to connect with doctors in realtime via their mobile devices. Today, the startup is announcing a significant update to their interactive mobile health network, including a suite of new apps for the iPhone, iPad, Android and the Web, and a revamped, cleaner UI.

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Couple held by Somali pirates returns to S. Africa

South African Deborah Calitz, reacts as she greets a family member upon their arrival with partner Italian Bruno Pelizzari, bottom right, whilst escorted by police officers at the OR Tambo International Airport in Johannesburg, South Africa on Wednesday June 27, 2012. The South African and Italian couple were held hostage for 20 months after being kidnapped in October 2010 from a yacht by Somali pirates. (AP Photo/Themba Hadebe)

South African Deborah Calitz, reacts as she greets a family member upon their arrival with partner Italian Bruno Pelizzari, bottom right, whilst escorted by police officers at the OR Tambo International Airport in Johannesburg, South Africa on Wednesday June 27, 2012. The South African and Italian couple were held hostage for 20 months after being kidnapped in October 2010 from a yacht by Somali pirates. (AP Photo/Themba Hadebe)

Deborah Calitz, center, and partner Bruno Pelizzari, bottom right, blow kisses towards family members as Maite Nkoana-Mashabane, Minister International Relations and Co-operation Minister, top right, looks on during their arrival at the OR Tambo International Airport in Johannesburg, South Africa on Wednesday June 27, 2012. The South African and Italian couple were held hostage for 20 months after being kidnapped in October 2010 from a yacht by Somali pirates. (AP Photo/Themba Hadebe)

Deborah Calitz, center, and her partner Bruno Pelizzari, bottom center, reacts as escorted by police officer upon their arrival at the OR Tambo International Airport in Johannesburg, South Africa on Wednesday June 27, 2012. The South African and Italian couple were held hostage for 20 months after being kidnapped in October 2010 from a yacht by Somali pirates. (AP Photo/Themba Hadebe)

JOHANNESBURG (AP) ? A South African woman and her Italian partner were handcuffed throughout the nearly two years they were held by Somali pirates, who fed them little but rice, pasta and bread, the now-freed couple said Wednesday after arriving in South Africa.

Deborah Calitz and Bruno Pelizzari, captured in late 2010 from a yacht off the coast of Tanzania, spoke to reporters at an emotional Johannesburg airport news conference. They were freed in Somalia last week and stopped in Italy to see Pelizzari's family before coming to South Africa, where friends and relatives draped in yellow ribbon printed with the word "believe" greeted them at the airport with tears, hugs and flowers.

"We were treated like untouchables" in Somalia, Calitz said. "We were treated worse than animals at times."

The two were held captive 20 months, among the longest periods hostages have been held by Somali pirates.

Relatives have said the two were sailing on a budget after buying a used yacht several years ago to pursue a dream of traveling the world's seas. At the time they were kidnapped, they were working for another South African yachtsman to earn money for a visit home.

The pirates originally demanded a ransom of $10 million, which relatives had said they could not pay. Their relatives in South Africa sought donations and organized concert fundraisers, and said the pirates kept changing their demand.

"Thank you for not giving up on us," a tearful Calitz told her friends and relatives Wednesday. She also thanked the governments of South Africa, Somalia and Italy.

"We're home! We're safe! And we're happy!" she said.

Calitz said Wednesday the couple did not know whether a ransom was paid. Last week, Somalia's defense minister said Somali security forces helped secure the release. He did not describe it as a rescue, but would not say if a ransom was paid. Most such cases end with payment of multi-million dollar ransoms, which security experts say only inspires more hostage-taking.

South Africa's foreign minister, Maite Nkoana-Mashabane, who met the couple at the airport Wednesday, told reporters the hostage-taking could only end once stability was brought to Somalia. Somalia has been beset by decades of civil war, and its last fully functioning government collapsed in 1991, allowing piracy and other crime to flourish. In more recent years, al-Qaida-linked militants have gained a foothold in the Horn of Africa nation.

Pelizzari echoed the South African foreign minister's calls for peace.

"We've created a rainbow nation in South Africa," he said, referring to the negotiated, peaceful end to white racist rule here. "We've got to do the same for the world."

Associated Press

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Auto Loan Financing - Smart Financial Decisions

When you need to buy a new or used car in today's economy, you might be afraid of making the kind of financial decision that you could end up paying for years into the future. If you are hoping to be relieved from this fear, you should know that the bad news is that this is a perfectly rational fear. The truth of the matter is that the economy is more volatile than it has been for decades, and the banks and major lenders are feeling the stress. People just like you are also feeling the stress, since they fear that they might lose their jobs at any moment. The thing about a car loan, however, is that if you need one immediately, there are really no reasonable substitutes. Public transportation doesn't work all of the time, especially if you have a family with children. This means that you are going to have to give your auto loan financing some serious thought.To begin with, the first step when you are planning your auto loan financing is to get your own finances in order. Now, this can mean different things to different people. Some people are going to have thousands of dollars in credit card debt to pay off. Others are going to have virtually no credit but steep day to day expenses. Whatever your situation is, it's important that you understand that you first have to add up your monthly household income. The next thing you have to do is figure out your monthly expenses. Don't forget to put money aside for living and lifestyle costs. Only you can know what you really spend on luxuries and the like in a month.Once you have a number for your auto loan financing, you will be more empowered to make the smartest decision. The last thing you want to do is lie to yourself about the kind of money you make. Remember that your money has nothing to do with your perception. It's all about the cold hard numbers. Once you have this number, you are an empowered consumer who can make the smartest possible decisions. Your next step then is going to be to find an online lender. The answer to this problem is probably going to be something you don't expect.Instead of going to a bank or major lender for your auto loan financing, you need to go online. The internet, believe it or not, is the best place to find the best deals on monthly car loan payments. Not only will you find affordable payment plans online, but you will also be able to find out if your application is accepted almost immediately. You will enjoy the speed, the convenience, and the low monthly payments.

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LevelUp Studio introduces Peti, a free puzzle game for Android

Most folks will know the name of LevelUp Studio from their Plume and Beautiful Widgets apps but they've gone ahead and ventured into a new area with their latest release. Yup, gaming is now on the developers list and as such they've now unveiled a pretty fun and free puzzle game called Peti.

Peti (People for Ethical Treatment of Invaders) will place you in a new world wherein you must save aliens that fall to Earth and send them back to their mother, all in an effort to keep her happy so that she doesn't destroy all of humanity.

Overall, the game will feel familiar you to you as it takes on a retro style much like Tetris or Dr. Mario but given that it adds plenty of new twists, achievements and special powers to make it more than a "drop and place" puzzle game, it's certainly one to check out.

The graphics and characters are fun, the game itself is challenging plus, it's free. For a first run at gaming, I'd say LevelUp Studio did quite well. Grab the download, check out the game trailer below and let us know what you all think of Peti in the comments.

Download Peti

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News Summary: Stocks bounce back; bank stocks rise

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Why Should You Get Tested for Colorectal Cancer? - West Hills ...

Last updated 1 day 5 hours ago

Colorectal cancer is a common form of cancer that originates in the colon or rectum, at the end of the gastrointestinal tract. Like many other forms of this deadly disease, colorectal cancer may not cause symptoms until it is at a more advanced stage. For this reason, it is extremely important for all men and women to get screened at their physician?s recommendation.

This video from the Centers for Disease Control and Prevention provides more information about the importance of colorectal cancer screening. By watching, you can learn more about the common misconceptions associated with this disease and why many people avoid or delay their screening.

Getting screened for cancer can help to detect the disease at its earliest, most treatable stages. To find out more about your recommended screening schedule, contact the experts at West Hills Hospital & Medical Center at (818) 676-4321.?

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Euro 2012: Irish soccer fan in Poland goes missing

By MONIKA SCISLOWSKA

Associated Press

Associated Press Sports

updated 8:45 a.m. ET June 19, 2012

WARSAW, Poland (AP) - A 21-year-old Irish soccer fan has gone missing while in Poland for the European Championship, local police said Tuesday.

James Nolan of Blessington, County Wicklow, was last seen early Sunday in the northern city of Bydgoszcz after watching games in fan zones and visiting local bars with a group of Irish friends.

Police spokeswoman Monika Chlebicz said that friends realized that Nolan did not return to their hotel, and he is not answering calls. They notified police, who are conducting a search of the city and have posted photos of Nolan on their website. The local media in Bydgoszcz and in the western city of Poznan have also shown images of Nolan.

Irish Ambassador Eugene Hutchinson was traveling to Bydgoszcz on Tuesday to be on hand for the search.

Nolan and a group of around 10 Irish friends arrived in Bydgoszcz on Saturday, making a stop en route from Gdansk to Poznan, where Ireland was playing matches against Croatia and Spain, said Krzysztof Schramm, deputy honorary consul of Ireland in Poznan. While in a bar, they probably got involved in a hostile dispute with a group of Poles, Schramm said.

Chlebicz didn't confirm this and said that Nolan's friends were still being questioned by police, but that there was no mention of trouble with Poles in their initial testimony.

The Irish group split up at night and when they next met, they realized that Nolan was missing, Schramm said.

Nolan studies environment engineering at Tallaght Institute of Technology in Dublin.

? 2012 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

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Video: Monks turn on modern charm

Mom who saved kids from tornado: ?It was instinct?

Though she selflessly shielded her two young children from a tornado while being battered to within an inch of her life, Stephanie Decker says she?s not a hero; the simple title "mom" fits her just fine. ?It was instincts and protecting my children,? she said Wednesday.

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US Olympic horses travel to London in style

FILE - In this Aug. 12, 2008 file photo, Gold medalist, German rider Hinrich Romeiker, celebrates with his horse Marius after winning the Eventing Individual at the Beijing 2008 Olympics Equestrian in Hong Kong. Bringing horses across the Atlantic for Olympic equestrian competition is a logistical feat _ one small example of the many people and efforts under way in the shadows to make the games go off without a hitch. (AP Photo/Kin Cheung, File)

FILE - In this Aug. 12, 2008 file photo, Gold medalist, German rider Hinrich Romeiker, celebrates with his horse Marius after winning the Eventing Individual at the Beijing 2008 Olympics Equestrian in Hong Kong. Bringing horses across the Atlantic for Olympic equestrian competition is a logistical feat _ one small example of the many people and efforts under way in the shadows to make the games go off without a hitch. (AP Photo/Kin Cheung, File)

LONDON (AP) ? They didn't have to absolutely, positively get them there overnight, but when the U.S. Equestrian Federation sent some of its horses to London for the Olympics, it was a special delivery.

The elite U.S. three-day eventing equine squad landed in London on Monday on a FedEx flight, having taken the red eye from Newark, N.J. They're not the first competitors to arrive as the countdown to the games clicks to less than 40 days away, but they are among the most pampered.

"They are all special," said Tim Dutta, who owns the international horse transport company that organized the trip. "We are working on everybody's dream."

Bringing these elite athletes across the Atlantic Ocean is a logistical feat ? one small example of the many people and efforts under way behind the scenes to make the games go off without a hitch. This is particularly true for horses ? the only animals that take part in the games, which start July 27 and end Aug. 12.

Let's just start by saying that these 10 are not just any old group of horses. These animals have passports that would be the envy of any human wishing to travel the world. That said, they get used to traveling, and most of the time, they don't ask for much ? not even an in-flight meal.

But grooms traveling with Twizzel, Mighty Nice, Arthur and the other seven horses that made the journey would maybe give them a bit of hay.

Horses like these can move in their boxes quite a bit, unlike human sardines on regular flights. But in case any of them gets bothered by the noise, the grooms might stuff some cotton in their ears, says Dr. Brendan Furlong, the veterinarian for the American eventing team.

Carrots are always a good way to calm any horse who gets nervous ? or even a horse tranquilizer in the rare case a prized animal gets really edgy. The goal is to get them to London stress-free.

As for the grooms, the vet, and the other humans that cater to these pampered prancers, well, they aren't exactly going first class. Furlong says he'll usually ask the pilots to keep the plane kind of cool, so sometimes this crowd finds itself wrapped in blankets to keep warm. There's no in-flight movie, so jokes about whether they choose between "Seabiscuit" or "War Horse" don't really cut it.

"It's not a job for the faint of heart," Furlong said. "You need to have someone who is a very confident flier and who can intervene quickly to calm a stressed horse."

After all, 1,200 pounds (544 kilograms) of stressed horse can be an intimidating prospect.

Furlong says the crews are usually very accommodating ? and always want to come back even briefly to see their precious cargo.

But even these horses didn't escape Britain's strict rules on quarantine. Furlong arranged to have a farm near Newark International Airport set up as a special quarantine area to comply with the U.K.'s rules ? though admittedly the cherished 10 only needed five hours of intense scrutiny to meet the criteria. Nothing but the best for this crowd. Really.

But do they know ? do the horses know that it's the Olympics? That it's a special event that happens only every four years?

Dutta swears they do.

"They're athletes," Dutta said of horses that jump big big fences and run oh so fast. "They love what they do."

Associated Press

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Syrian activists report renewed shelling in Homs

In a Tuesday, June 5, 2012 photo, a Syrian man stands next to a grave of 40 Syrians were killed in a military raid by the Syrian army in April 2012, in the town of Taftanaz,15 kilometers east of Idlib, Syria. At dawn on April 3, Syrian forces shelled the town in the first volley of what residents say was a massive assault after a string of large protests calling for the end of the autocratic rule of President Bashar Assad. (AP Photo/Khalil Hamra)

In a Tuesday, June 5, 2012 photo, a Syrian man stands next to a grave of 40 Syrians were killed in a military raid by the Syrian army in April 2012, in the town of Taftanaz,15 kilometers east of Idlib, Syria. At dawn on April 3, Syrian forces shelled the town in the first volley of what residents say was a massive assault after a string of large protests calling for the end of the autocratic rule of President Bashar Assad. (AP Photo/Khalil Hamra)

Protesters chant slogans against the Syrian regime and Russia's support of President Bashar Assad as they burn a banner depicting Assad, top, his brother, Maher Assad and Russian President Vladimir Putin, bottom, in the southern port city of Sidon, in Lebanon, Sunday, June 17, 2012. (AP Photo/Mohammed Zaatari)

FILE - In a Tuesday, June 5, 2012 file photo, an elderly Syrian man stands on the side of a street in the town of Taftanaz, 15 kilometers east of Idlib, Syria. At dawn on April 3, Syrian forces shelled the town in the first volley of what residents say was a massive assault after a string of large protests calling for the end of the autocratic rule of President Bashar Assad. (AP Photo/Khalil Hamra, File)

BEIRUT (AP) ? Syrian activists say government forces have renewed shelling in the central city of Homs.

Monday's violence comes a day after the head of the U.N. observers' mission in Syria demanded that warring parties allow the evacuation of women, children, elderly and sick people endangered by the fighting in Homs and other combat zones.

The activist group Syrian Observatory for Human Rights cited witnesses on the ground as reporting the government shelling, along with gunfire and explosions.

Opposition groups say more than 14,000 people have been killed since the uprising began in March 2011. The Observatory says more than 3,400 soldiers and militiamen loyal to the government have also been killed.

Associated Press

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Facebook suggests Nasdaq glitches led to decline

NEW YORK (AP) ? Facebook is suggesting that trading problems at the Nasdaq Stock Market contributed to a sharp drop in the company's stock price after its initial public offering.

In laying out a defense against dozens of lawsuits from disgruntled shareholders, Facebook and the banks overseeing the IPO also insist that nothing about its IPO process was illegal or even out of the ordinary.

The defense came in a court filing in which Facebook and the banks, led by Morgan Stanley, are seeking to combine the more than 40 federal and state lawsuits around the country into one federal case in New York.

The highly anticipated IPO was marred by technical glitches that delayed trading when Facebook went public on May 18.

Facebook said those glitches at Nasdaq hurt its stock for days. Seven of the lawsuits claim that Nasdaq errors created market uncertainty and caused shareholders to lose money. Nasdaq has admitted that there were technical problems. Nasdaq spokesman Joe Christinat declined to comment Friday.

The bulk of the shareholder lawsuits ? 28 ? center on Facebook's May 9 disclosure that the number of mobile users it has was growing faster than revenue. The lawsuits claim that analysts at those banks had discussions with Facebook after May 9 and had lowered their forecasts as a result, but disclosed the changes only to a handful of preferred clients.

In its filing late Thursday, Facebook said the lawsuits "ignore that what Facebook and (the banks) allegedly did both followed customary practices and did not violate any rules."

"As is customary," Facebook said, the May 9 filing "did not include any forward-looking projections." In other words, Facebook did not give a revenue or profit forecast in its amended filing, nor did it do so in any other IPO document. Facebook added that federal regulators do not require companies to give earnings or revenue projections in their IPO documents.

Facebook said it wants to bring the lawsuits to New York in part because that's the home to most of the banks involved in the IPO. It's also where many of the events in dispute took place and where Nasdaq is headquartered.

In separate filings with regulators Friday, Facebook released letters it exchanged with the Securities and Exchange Commission in the months leading up to IPO. That's something companies typically do after a confidentiality period ends.

Among other things, federal regulators had wanted to know more about the revenue it gets from mobile devices, its $1 billion deal to buy Instagram and the control CEO Mark Zuckerberg has over the company. Facebook amended its regulatory documents several times before the IPO, but the communications leading to those changes weren't public until now.

On an upbeat note, Facebook's stock gained value for the week for the first time. The stock climbed $1.72, or 6.1 percent, to close at $30.01 on Friday. That's up nearly 11 percent for the week, though it's still down 21 percent from its IPO price of $38.

Also on Friday, Facebook's chief technology officer, Bret Taylor, announced that he is leaving the company to work on a startup. Taylor said on his Facebook profile that he's "sad to be leaving, but I'm excited to be starting a company with my friend Kevin Gibbs." Taylor joined Facebook in 2009 when the company bought FriendFeed, the Internet company where he was working at the time.

___

AP Business Writer Christina Rexrode contributed to this story.

Associated Press

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Egypt votes to choose successor to Hosni Mubarak

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Kids With Autism Face Health Care Disparities, Study Finds

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Cheap Domain Registration India, Web Hosting India, SSL ...

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Overfed fruit flies develop insulin resistance; Represent new tool to study human diabetes

Overfed fruit flies develop insulin resistance; Represent new tool to study human diabetes

Tuesday, June 5, 2012

With Type 2 human diabetes climbing at alarming rates in the United States, researchers are seeking treatments for the disease, which has been linked to obesity and poor diet.

Now biologists at Southern Methodist University, Dallas, report they have developed a new tool that will help researchers better understand this deadly disease.

By manipulating the diets of healthy adult fruit flies, the researchers developed flies that are insulin-resistant, a hallmark of Type 2 diabetes.

Until now, researchers largely have relied on rats, mice and other animals as model systems for exploring the metabolic and genetic changes that take place in diabetics.

The fruit fly Drosophila melanogaster has been widely deployed in labs to investigate a wide range of human diseases, from Alzheimer's to cancer. But the scientific literature hasn't documented use of the adult fruit fly for studying the metabolic disruptions that are the hallmark of Type 2 diabetes. The fruit fly's advantages include its low cost and a very short lifespan, both of which enable scientists to undertake rapid screenings in their search for new genetic and drug treatments.

The insulin-resistant fruit fly was developed in the lab of SMU biologist Johannes H. Bauer, principal investigator for the study. It was accomplished by feeding fruit flies a diet high in nutrients, said Bauer, an assistant professor in SMU's Department of Biological Sciences. That process mimics one of the ways insulin resistance develops in humans ? overeating to the point of obesity.

The lab's insulin-resistant fruit flies now can serve as a highly relevant and efficient model for studying Type 2 diabetes.

"We learned that by manipulating the nutrients of fruit flies, we can make them insulin resistant," Bauer said. "With this insulin-resistant model we can now go in with pinpoint precision and study the molecular mechanisms of insulin resistance, as well as drug treatments for the condition, as well as how to treat obesity, how to block insulin resistance and how metabolic changes from a specific diet develop. The possibilities are endless."

The researchers reported their findings in the article "Development of diet-induced insulin resistance in adult Drosophila melanogaster," published in Biochimica et Biophysica Acta - Molecular Basis of Disease.

Two overfeeding diets, carb and protein, both result in insulin resistance

Insulin, produced by the pancreas, is the hormone that tells our cells to absorb glucose, a necessary sugar molecule that provides our body, particularly the brain, with the energy to function, make repairs, move and grow.

In Type 2 diabetes, a person is insulin-resistant because his or her cells fail to respond to insulin's signal to absorb glucose. The disregulation of glucose upsets the body's delicate internal equilibrium, causing massive disruptions in normal cellular processes. These interruptions manifest in multiple disease symptoms, making Type 2 diabetes difficult to characterize, treat and cure.

To provide a good base model organism to study aspects of this complex disease, researchers in the Bauer lab wanted to determine whether flies develop diabetes-like metabolic changes when fed different diets. The researchers developed the insulin-resistant flies in two different ways: One group of fruit flies was overfed a carbohydrate-loaded diet; a second group of flies was overfed a protein-loaded diet. In both cases, the disruption had a profoundly detrimental effect on the flies' health and physiology.

SMU biologist Siti Nur Sarah Morris, lead author on the study, said the results the researchers observed were both expected and unexpected. The researchers expected the flies to gain weight, which they did. Carb-loaded flies gained excessive weight and got fat, just like humans who overeat sweets, french fries, pasta and ice cream. Protein-loaded flies also gained weight, but upon extreme overfeeding they lost weight, just like humans who follow the popular Atkins Diet, a weight loss program in which participants eat meat, seafood and eggs.

The researchers expected the carb-loaded fruit flies to develop insulin resistance, which they did.

In a surprising result, however, the fruit flies that overate protein also developed insulin resistance, but at a faster and more severe rate.

"Carb-loaded flies gain weight. Protein-loaded flies gain and then lose weight. So the two diets have exactly opposite effects on metabolism," Bauer said. "But too much of either one of them causes insulin resistance. That surprised us."

Researchers at Southern Methodist University, Dallas, demonstrate that adult fruit flies fed either high-carb or high-protein diets develop metabolic abnormalities, including insulin resistance, which is a hallmark of Type 2 human diabetes. For decades, fruit fly D. melanogaster has been used successfully to investigate multiple human diseases from Alzheimer's to cancer, but not diabetes. This new study demonstrates that diet profoundly influences fruit fly physiology and health and that insulin-resistant flies provide a new research tool for investigating the molecular mechanisms of insulin resistance. Credit: SMUResearch.comOverfed flies had shortened lifespans, differences in fertility

In other findings, carb-loaded flies experienced a profound decline in egg-laying, a measurement of fertility. In contrast, protein-loaded flies first experienced increased egg-laying, but the extreme diet led to decreased egg laying. Both diets led to shortened longevity, the scientists reported.

"The high-protein flies looked frail and unhealthy. They moved less, almost as if sedated," Morris said. "The fatter flies on the high-carb diet had massively decreased fertility; they flew less but still tried to move."

While both diets resulted in insulin resistance, differences were remarkable.

"The carb data imply a linear relationship between carb levels and health. The more carbs, the more weight, the more sugar storage and fat, the more insulin resistance and the less fertility," Bauer said. "But with protein, this relationship becomes parabolic, meaning all readouts go up, then come down again. The decreased storage we liken to a catabolic state that is primarily destructive for the body's optimum metabolic functioning, such as the ketosis typically seen in people eating Atkins-type diets."

###

Article: http://www.sciencedirect.com/science/article/pii/S0925443912000993

Southern Methodist University: http://www.smu.edu

Thanks to Southern Methodist University for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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A Pill to Prevent Skin Cancer? | SRxA's Word on Health

Summer, it seems, has finally arrived.? And with it comes long lazy days at the beach, the pool? and, unfortunately, the associated risk of skin cancer. ?To guard against this we all know to limit sun exposure, use high factor sunscreen and seek shade. But now it seems there?s one more thing we can do to help safeguard ourselves ? take Advil!

Really? ? Yes, it would appear so. ?According to a case-control study published in the journal Cancer, the use of non-steroidal anti-inflammatory drugs (NSAIDs) is associated with reduced risk for skin cancer.

Using health registries, researchers identified 18,500 cases of skin cancer among adults in northern Denmark and matched them to population controls without skin cancer. Patients who had ever used NSAIDs (more than two prescriptions) had a 15% reduced risk for squamous cell carcinoma and a 13% reduced risk for malignant melanoma compared with those who had two or fewer prescriptions; especially when the drugs were taken for seven or more years or at a high intensity.

The risk reduction was seen in patients taking aspirin, NSAIDs, and COX-2 inhibitors, such as Celebrex.

Individuals who took NSAIDs did not appear to gain a generally reduced risk from developing basal cell carcinoma, although they had a 15% and 21% reduced risk of developing this kind of cancer on less-exposed sites (areas other than the head or neck) when taken long term or at a high intensity, respectively.

So how do NSAIDs do it? ?The authors suggest that they reduce the risk of skin cancer by blocking COX enzymes, which are involved in the inhibition of apoptosis ?and in stimulating angiogenesis. Or, in plain English, these anti-inflammatory drugs counteract the enzymes involved in the important steps of cancer development such as inhibition of cell death and suppression of the immune system.

Despite the positive results, lead author Sigr?n Alba Johannesd?ttir from Aarhus University Hospital cautions, ?because there are also risks associated with the use of NSAIDs, we cannot give recommendations on NSAID use in general. It is up to the patient and his or her physician to balance benefits and harms associated with use of the medications.?

Nevertheless, when viewed alongside the study results?fom earlier this year that showed patients who took aspirin daily for at least three years were 36% less likely to develop metastatic cancer and 15% less likely to die from the disease, this can only be good news.

Especially for people like me, who love the sun and can?t make it downstairs without a morning dose of diclofenac!

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Poll: Political independents outweigh partisans

WASHINGTON (AP) ? Call it a pox on both the Republican and Democratic houses.

More Americans now call themselves politically independent than at any point in the last 75 years, according to a new poll. The survey also shows that those who do align themselves with a party are more ideological and have become more polarized than at any point in the last 25 years, particularly on issues important in this year's presidential and congressional campaigns.

Party loyalty, however, only goes so far; neither Republicans nor Democrats say their own party is doing a good job standing up for its traditional positions.

Five months before the November elections, the Pew Research Center poll released Monday sheds light on how the electorate feels about the nation's two major political parties. And sour seems to be an understatement.

The results indicate a collective thumbs down to both the Democratic and Republican Party, showing that an unprecedented 38 percent of adults rejected both parties and call themselves independents. Only 32 percent now say they are Democrats and 24 percent now call themselves Republicans.

This flight away from the two major political parties began in 2008, a time of intense partisanship as President Barack Obama battled Republican Sen. John McCain for the White House.

Then as now, independent voters are a critical constituency that candidates must win over to prevail in competitive general elections.

Exit polls show these voters have sided with the winning candidate in all but two of the past 10 presidential elections. Independents broke for Obama, 52 percent to 44 percent for McCain four years ago. And recent polling suggests independents are about evenly divided now between Obama and Mitt Romney, his likely Republican rival.

Independent voters also have been on the winning side in congressional contests eight out of nine times since the 1994 election, when Republicans took control of the House for the first time in 40 years.

So both Republicans and Democrats are making serious plays to win them over.

The survey found that the face of the independent voter also is changing, posing challenges for Democrats.

More Hispanic and younger voters ? key Democratic voting blocs ? say they are politically independent and Republicans are aggressively courting them.

Hispanics who describe themselves as independents have jumped from 31 percent in 2006 to 46 percent now. And nearly half of Americans born since 1981 now say they are independents.

To be sure, 56 percent of Americans still identify themselves as a member of either the Democratic or the Republican parties.

But the parties are pushing out those in the ideological middle.

The vast majority of Republicans, 68 percent, say they are conservative, up from 60 percent in 2000. And the conservative Democrat has become scarce as the share of self-described liberals in the party has grown 10 points since 2000, from 28 percent to 38 percent. As the moderates abandon both parties, the poll finds partisans' views on the major issues in this year's campaign have become more deeply polarized since the Pew Center first measured those views in 1987.

The poll measured opinions on 48 different questions about basic political values, and found Democrats and Republicans farther apart than at any point since 1987.

The sharpest differences between partisans fall mostly on the issues at the core of this year's campaign regarding government's role and effectiveness: whether regulation helps or hurts business, how involved government should be in people's lives and whether government programs are effective or wasteful. Sharp differences also centered on the question of how much of a "social safety net" government should provide ? whether government should make sure every citizen's basic needs are met or take care of those in need even if it means more debt.

Shifting opinions on these issues are not limited to core partisans: Independents who lean toward either Republicans or Democrats are also more sharply polarized from each other than they were 25 years ago, particularly on how much government should do and how effective it is.

Obama holds a slim edge over Romney in the poll, 49 percent to 45 percent, among registered voters, and the results suggest the sharpest divides between Romney and Obama supporters are over the role and effectiveness of government.

About one-fourth of voters are "swing voters," or those who are not firmly committed to a candidate. Ideologically, this group is closer to Romney on the social safety net, but closer to Obama on social issues and questions about labor unions. They fall about evenly between the two on the role of government.

The poll also found a liberal shift on social issues in recent decades, with fewer saying they hold old-fashioned values about family and marriage, or the role of women.

The Pew Research Center 2012 Values Survey was conducted by telephone April 4-15 among a random national sample of 3,008 adults. Interviews were conducted by live interviews and respondents were reached on landline and cellular telephones. The margin of sampling error for results based on all interviews is plus or minus 2.1 percentage points.

___

Follow Jennifer Agiesta on Twitter at http://www.twitter.com/jennagiesta

Associated Press

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UK queen goes to the races as celebrations begin

Queen Elizabeth II spent the first day of her Diamond Jubilee Weekend at the races in Epsom, England, a tradition older than Kentucky Derby. NBC's Michelle Kosinski reports.

By Reuters

LONDON -- Four days of celebrations to mark Queen Elizabeth's 60 years on the British throne was getting under way on Saturday with one of her favorite pastimes -- a trip to the horse races.?

Hundreds of thousands of people are expected to descend on London over the next few days for Diamond Jubilee festivities, with millions attending street parties across the country as the nation marks the queen's personal milestone.?

---

"The queen has given incredible service," British Prime Minister David Cameron said. "She's never put a foot wrong, she's hugely popular and respected here and around the world and it's an opportunity for people to give thanks and to say thank you for the incredible service that she's given."?

Queen Elizabeth II is celebrating 60 years on the throne. Watch archival footage from her childhood and ascension to the throne to the present day.

Across much of Britain, red, white and blue "Union Jack" flags billow from street lamps, outside buildings, shop fronts and houses, and sales of patriotic souvenirs have rocketed ahead of the celebrations.?

To royalists, the occasion is a chance to express their thanks and appreciation to the 86-year-old Elizabeth, head of state for 16 countries from Australia and Canada to tiny Tuvalu in the Pacific Ocean, for her years of public service.?

Secret donors, foreign firms bankroll UK's Diamond Jubilee celebration

For others, the chance of some extra days off work and to enjoy the sort of extravaganza and public ceremony for which Britain is renowned has made it a welcome break from austere times, pay freezes and deep public spending cuts.?

Republicans hope the occasion marks the last hurrah of a dying anachronism, while some 2 million people are leaving Britain altogether to go on holiday.?

"Original jubilees were invented in the 19th century by the popular press as modes of national celebration for which the monarchy and monarch was almost incidental," royal biographer Robert Lacey said.?

Jubilee fever is gripping the U.K. in the form of royal souvenirs ? but the ultimate Jubilee gift may be a one-of-a-kind desk complete with a hidden diamond, which will be auctioned off for charity. NBC's Ben Fogle reports.

He said the jubilee was as much about society celebrating itself as it was about the head of state and the now largely symbolic institution of the monarchy.?

"They tend to work best in times of economic hardship. It provides a tonic for the country," Lacey told Reuters.?
?

Jubilee treat: Canadian Mounties guard Britain's queen

Having acceded to the throne in February 1952 on the death of her father George VI when Winston Churchill was prime minister, Elizabeth is now the longest-lived British monarch.?

Only her great-great-grandmother Victoria spent longer on the British throne and she looks on course to overhaul her as longest-serving monarch in 2015.?

While more than a century separates festivities marking Queen Elizabeth II's 60 years on the throne from those honoring her predecessor Queen Victoria, surprising similarities connect the commemorations. NBC News' Jim Maceda reports.

As well as being head of the Commonwealth of nations mainly made up former British colonies, Elizabeth is also the Supreme Governor of the Church of England.?

"I think we've been enormously fortunate in this country to have as our head of state a person who has a real personality - a personality that comes through more and more, I think, in her public utterances," said the Archbishop of Canterbury Rowan Williams, the spiritual head of the Anglican Church.?"Someone with insight and judgment, and with immense stamina and a depth of commitment that I think is immensely impressive to all of us."?

The four days of celebrations begin on a fairly low-key note when the queen indulges her long love of horses by attending the Epsom Derby, one of the biggest events in the British horse racing calendar.?

On Sunday, there will be a flotilla of 1,000 boats assembled from around the globe travelling 25 miles along the River Thames featuring the queen and her 90-year-old husband Prince Philip on a royal barge, in the largest such pageant for 350 years.?

Thousands of street parties are also planned across Britain, including one on Downing Street outside Cameron's office, as part of a "Big Jubilee Lunch".?

With just days to go until the country's largest river event in 350 years, a complex security operation has kicked in to ensure the safety of the thousand boats that will accompany the Queen down the Thames for the Jubilee river pageant. The flotilla will include sailing ships, music barges and a Hawaiian war canoe. ITN's Fatima Manji reports.

Officials say there are some 9,500 street parties planned in England Wales and ABTA, the British travel association, said almost 2.5 million Britons were expected to take part.?

London's Heathrow airport said some 780,000 people were due to arrive in the next few days, although ABTA said an estimated 2 million Britons were planning to head overseas to take advantage of the two extra public holidays.?

The queen's London residence Buckingham Palace will play host to a pop concert on Monday featuring the likes of Paul McCartney and Elton John, before a network of 4,200 beacons will also be lit across Britain with more set alight around the Commonwealth.?

The celebrations culminate on Tuesday with a memorial service at St Paul's Cathedral, a carriage procession through central London and flypast by present and former royal air force aircraft.?

Police said the weekend would include the largest royal security operation ever conducted. Some 13,000 officials including about 6,000 police officers will be on duty for the Thames pageant, which poses challenges never before encountered.?

"We're treating it as a unique event, to have that many dignitaries on that many boats moving along the Thames," London police's Deputy Assistant Commissioner Stephen Kavanagh told Reuters.?

More world news from msnbc.com and NBC News:

Follow us on Twitter: @msnbc_world

Copyright 2011 Thomson Reuters. Click for restrictions.

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London Baby, toddler, child family events, workshops, art, concerts ...

Jun 2, 2012 by admin

Spotted Zebra, London?s premier bespoke nanny agency, has begun offering Pop-up Nurseries around London: Clapham, Queen?s Park, Newington Green.? Book in 48 hours in advance, leave your child in a small nursery cared for by a 3:1 staff of highly qualified nannies.?

Take Stars Gym and Creche up on their fantastic offer to try out their gym and cr?che.? Pay what you like, try it for free, try it for ?5, take a look around and see if you could use Stars gym to keep up your current fitness levels or improve. ?Monday ? Friday: 9:30 ? 11:30 Ofsted registered cr?che, very clean, very kind, very good, for 0-5 Review

?Half Term Activities, Workshops, Events:

?Royal Procession from The Palace of Westminster to Buckingham Palace. Monday, 4^th June 2:20.? HRH Queen Elizabeth and her most royal posse will be travelling by gilt and golden carriage through the streets of Westminster.? Check out the procession route and timings.? Balcony appearance and fly by included!!

?British Museum: Horses, Hawks and Hounds Half Term Family Event.? Monday, 4^th ? Friday 8^th June; 11:00-4:00pm.? Come to the Great Court and take part in a variety of activities including Falconry demonstrations, make a clay horse, take part in a royal procession ? check the daily programme for events before you set out.?

?V and A: Make-It Calligraphy.? Monday 4^th ? Thursday 7^th June, 10:30 ? 12:30 & 2:00-4:00.? Bring the family and take part in a two hour artist-led workshop.? In the past, my 6 and 3 year old have enormously enjoyed these events.? ?5 per child, booking required.

There is also an imagination station craft activity on each day, if you can?t make the workshop.?

?Wallace Collection

• Fabulous Furniture, Wednesday 6 June, 10.30am ? 12.15pm & 2pm ? 3.45pm Free, drop-in art workshop. Ages 5+. Children must be accompanied by an adult. Come and draw swags, swirls, flowers and the dancing monkeys that grace our wonderful decorative gilded brass and turtle-shell furniture. Then make your own collage pattern in gold and bright jewel colours with the help of artist William Riding.?
• ????????? Rubbing Shoulders with a Knight in Shining Armour, Thursday 7 June, 10.30am ? 12.30pm & 2pm-4pm. Ages 7+ Cost ?7 per child. Children must be accompanied by an adult. Accompanying adults free. Bookingessential on 020 7563 9527 or booking@wallacecollection.org? Limited places still available! Explore the armouries and try on original and replica armour then spend time with the Wallace Collection?s Brass Rubbing knight! Artist Gilly Gretton will teach you how to make a brass rubbing, and then how to turn it into a self-portrait, using collage, of yourself as a knight (or lady).

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?Saatchi Gallery: Family Art Workshops, Sunday 3^rd ? Tuesday 5^th June, 11:00am and 3:00pm.? Come join artist Valeria Amadei in the Saatchi Gallery for a gallery walk and then make a self-portrait or celebrate the Jubilee and make a royal portrait.? ?5 per child, book ahead: contact Valeria familyartworkshops@gmail.com or 07794727062

?National Gallery: Royal Regatta and Jubilee Art Labs: Monday 4^th and Tuesday 5^th June, 11:00-3:00, drop-in.? Join Harriet Hill and Marc Woodhead and create your own boat to sail across the gallery (or take home).? A wonderful way to create a quality artefact from the events going on in Westminster.? Free, tickets allocated half-hour before start.? Ages 5+ with younger siblings welcome.

?Gate Picturehouse, Tales of the Night: various times and dates over half-term.? Come and see the latest from the creator of the magical and pensive Kirkou.? Tickets ?8.50 for adults, and ?5.50 children.?

?Holland Park Ecology Centre: half term activities.? Wednesday 6^th ? Friday 8th June, 10:00 ? noon and 2:00-4:00pm daily.? Your kids will take part in well-organised activities where they create a wilderness shelter, use a compass, collect mini-beasts, plant herbs ? well-staffed, well-resourced and just a fabulous way to spend a morning or afternoon.? Over 8?s can be left.? Ages 5+, ?4 for RBKC residents, ?5 for non-residents.? Book early to avoid disappointment.?

?Greenwich National Maritime Museum: June Half-Term Family Events. Monday 4^th ? Friday 8^th .? Bring the kids out and explore the historic River Thames by making your own pirate ship, meeting historic sea fearers, make a map, explore a royal barge and more activities.? A variety of activities for all ages, all free, most drop-in.

?Weekend Events for the Bigs, Smalls and the Whole Family:

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London Green Fair:? Come and enjoy a day of celebration, dance, debate, learning, singing, crafting, in Regent?s Park in the annual two-day London Green Fair.? The children?s area will have an interesting variety of activities including felting, planting, herb walk, make a tree sprite, textile workshops. Parents can take part in a Waldorf parenting workshop where Steiner teachers will be on hand to discuss parenting.?

?BP Saturday at Tate Britain: Saturday 9^th June, 10:00-3:00.? Come and enjoy a variety of activities for children around the museum.?? Create sound performances, create your own art to share ? for the entire family, free.?

Gate Picturehouse Kids Club: Tickets ?1 each for ?4 annual membership.? Great way to get some down-time over a busy morning of exploring the near-by Kensington Palace, Princess Diana Memorial Playground, Kensington Gardens, Notting Hill Farmer?s Market and more ..

Just for Babies:

NCT Kensington and Chelsea Bumps and Babies Group: Gymboree, Baden Powell House.? Every Tuesday 12:30 ? 1:45pm, if you are new to motherhood, or have a new baby, this is a fantastic way to meet other people in the exact same boat.? Its open to anyone, please drop by this welcoming and warm group.? If you have a little one, they will love playing on the very clean, very fun Gymboree equipment.? nctkensington@yahoo.co.uk.

Gate Picture House Notting Hill: Big Scream.? Come and enjoy a vintage theatre?s screening of Moonrise Kingdom with your infant.? Great chance to see current cinema without having to shell out for a sitter.? Nappy changing set up, dim lights so you can see what they are up to ? fabulous morning out.?

Baby and Toddler Events:

Classical Babies:? Wednesdays, 11:00am, Belisize Park, Interchange Studios. ?10 per family for a delightful classical concert that is completely baby and toddler friendly, the perfect mid-week bit of brain candy read more about the fabulous bit of motherhood: My review

Classics with my Baby: As seen in the Independent, Time Out, and Gramophone Magazine, this critically acclaimed concert series specifically designed for parents and children (0-5 years) to enjoy together. Tickets: Adults ?10, children FREE ( special offers for online tickets from website) Eat cake and mingle from 10:00am and concert begins at 10:30am. This is such a treat, easy to get to and worth every penny. My review

Baby and Toddler Classes

Culture Kids Music Class: Chelsea, Marylebone and Hampstead

Check out their new web site!! Come along for the most amazing, dynamic, invigorating, multi-sensory, multi-instrumented music class.? There is not the usual scrum for the shakers, every single kid gets a chime, ladybird game, sunglasses, gorgeous set of fairy wings, caterpillar costume ? there are literally scores of props that come out with each song. ?Further, these props all change the following week when the class explores a new theme. ?Read my review.?

If you ?like? Culture Kids on Facebook and write ?fabwebsite? on their wall, you will get a discount on your classes.? Check the schedule for times and prices and age groups.?

Classes for Big Kids

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Judo Classes at Stars Gym Wednesdays 4pm (4-8 years) and 5pm (8+) with prospective Olympians Jonathan Purssey and Alex Farbon.? Further, starting 3^rd April, the engaging Carlos Andrade will be teaching Kickboxing on Tuesdays, 4:30 (4-9 years).? Carlos?s class is drop-in, ?9 per session, so come along when you like and have fun!!

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